Neanderthals gave us disease genes

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Neanderthals gave us disease genes

Message  gerardM le Ven 31 Jan - 12:02

Hi everyone,

Anyone interested in Neanderthals?

-> Neanderthals gave us disease genes
Gene types that influence disease in people today were picked up through interbreeding with Neanderthals, a major study in Nature journal suggests.

They passed on variants involved in type 2 diabetes, Crohn's disease and - curiously - smoking addiction.

Genome studies reveal that our species (Homo sapiens) mated with Neanderthals after leaving Africa.

Similar links from the BBC Web site:


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Re: Neanderthals gave us disease genes

Message  gerardM le Ven 31 Jan - 17:31

Hi everyone,

Scientific American also posted on the subject
-> Sex with Neandertals Introduced Helpful and Harmful DNA into Modern Human Genome
Sex with Neandertals Introduced Helpful and Harmful DNA into Modern Human Genome

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Re: Neanderthals gave us disease genes

Message  gerardM le Dim 2 Fév - 20:31

Bonsoir à tous,

Si je me souviens bien, jusque là Neandertal nous avait donné 1-4 % de nos gènes (plus précisément, des gènes des humains non Africains)

Eh bien voila que maintenant, c'est 20 % !
-> Plus de Neandertal en nous ?
En comparant des génomes ancien et modernes, des scientifiques américains ont découvert qu’environ 20% du génome néandertalien persiste dans les populations humaines actuelles.

D'ici qu'on nous dise que les Neandertals sont encore parmi nous...

~~ édition
Je suis en train de lire...
Si je comprends bien, les 4 % sont le pourcentage de gènes en chacun de nous (hors Afrique), les 20 % représentent le pourcentage de la variété de tous les gènes.

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Re: Neanderthals gave us disease genes

Message  gerardM le Lun 3 Fév - 22:24


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Re: Neanderthals gave us disease genes

Message  MurielB le Mar 4 Fév - 8:55

Hi Gérard
Have you read the series Earth's children ? http://en.wikipedia.org/wiki/Earth's_Children
The books are about the period of co-existence between Cro-Magnons and Neanderthals. I have read them in French.
The clan are the Neanderthals and the others are the Cro-Magnons. It was very interesting to note their mental differences.

Physiologically, the Clan are heavier and broader but also shorter than the people of The Others. They are very slow to embrace change and to innovate, and they still chase after animals to spear them directly, whereas the Cro-Magnons are enthusiastic about innovation and have moved on to projectile spears. The Clan's tools, clothing, and household implements are similarly less refined and sometimes less effective than those of their Cro-Magnon counterparts, whose implements and other goods are more technologically sophisticated.
The Clan's reluctance to change is depicted by Auel as a function of their cognition; they are presented as dependent upon their racial-genetic memory. The average Clan child needs only be 'reminded' of a thing to know it permanently, though skilled tasks still require repetitive practice. Furthermore, the need to encode everything into a child's brain has increased the average Neanderthal head size to the point that, by the time of the first novel, women of the Clan are having trouble giving birth to their large-headed babies—a sign that their evolutionary strategy has run its course.

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Re: Neanderthals gave us disease genes

Message  MurielB le Mar 4 Fév - 14:17

Hi Everyone
Earth's children from Jean Marie Auel is very convincing because true to life.
http://www.jeanauel.com/about.php

She immersed herself in the available historical and scientific data, learning everything she could about life more than 30,000 years ago. Her extensive, precise research became a hallmark of her work, earning her the respect of archeologists, anthropologists, and paleontologists worldwide for her subtle interpretation of facts and artifacts

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